Table 1.
Functional outcomes after SCS and activity-based training
| Functional outcomes | Reported with SCS on |
Reported in | Time of first observation after surgery (SCS on) | Reported with SCS off | Reported in |
|---|---|---|---|---|---|
| Voluntary muscle contraction | 8/8 participants | Angeli et al. 2018; Gill et al. 2018; Wagner et al. 2018 | Day 1 |
4/8 participants AIS B/C/D |
Angeli et al. 2018; Wagner et al. 2018 |
| Single joint movements of paralyzed joints | 8/8 participants | Angeli et al. 2018; Gill et al. 2018; Wagner et al. 2018 | Day 1 |
2/8 participants AIS C/D |
Wagner et al. 2018 |
| Standing | 8/8 participants | Angeli et al. 2018; Gill et al. 2018; Wagner et al. 2018 | Week 1 |
4/8 participants AIS C/D |
Angeli et al. 2018; Wagner et al. 2018 |
| Treadmill walking | 8/8 participants | Angeli et al. 2018; Gill et al. 2018; Wagner et al. 2018 |
3/8 > Week 2 5/8 > Week 10 |
n.r. | |
| Overground walking |
6/8 participants (with assistance e.g. walker) |
Angeli et al. 2018; Gill et al. 2018; Wagner et al. 2018 | > Week 20 |
2/8 participants AIS C/Da (with assistance e.g. walker) |
Wagner et al. 2018 |
Included studies: Angeli et al. 2018 (NCT02339233), Gill et al. 2018 (NCT02592668), Wagner et al. 2018 (NCT02936453). Included participants (N = 8): 3 AIS A (motor and sensory complete), 2 AIS B (motor complete), 3 AIS C/D (motor incomplete)
aOne participant in Wagner et al. 2018 achieved steps overground without additional support 3 months after rehabilitation (parallel bars present for safety but not touched)