Table 2.
Predictive factors of OS
| Overall survival | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| Cut off | HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (years) | 60 | 1.053 | 0.552–2.008 | 0.875 | |||
| Tumor size (cm) | 5 | 2.018 | 1.003–4.06 | 0.049* | 0.751 | 0.205–2.753 | 0.666 |
| T stage | 3 | 1.696 | 1.081–2.662 | 0.022* | 1.421 | 0.707–2.856 | 0.323 |
| N stage | 3 | 1.507 | 1.115–2.038 | 0.008* | 2.18 | 0.875–5.433 | 0.094 |
| Pathologic stage | 3 | 1.02 | 0.751–1.384 | 0.612 | |||
| pT stage | 3 | 2.3 | 1.332–3.971 | 0.003* | 0.518 | 0.264–1.015 | 0.055 |
| ER score | 4 | 1.33 | 0.685–2.58 | 0.4 | |||
| PR score | 4 | 0.4 | 0.156–1.023 | 0.047* | 0.38 | 0.102–1.418 | 0.15 |
| HER2 score | 4 | 1.983 | 0.454–1.611 | 0.036* | 0.508 | 0.254–1.154 | 0.51 |
| KI67 score | 4 | 0.825 | 0.293–2.323 | 0.716 | |||
| P53 score | 4 | 1.024 | 0.541–1.939 | 0.475 | |||
| CPN1 score | 4 | 3.438 | 1.784–6.624 | < 0.001* | 2.384 | 1.073–5.295 | 0.033* |
HR: Cox proportional hazard ratio, 95% CI: 95% confidence interval
*Statistically significant (P < 0.05)