Table 1.
Comparison of the baseline data of study objects
| Parameters | Health (n = 30) | T2DM (n = 36) | DN (n = 32) | |
|---|---|---|---|---|
| Age (year) | 54.31 ± 4.81 | 55.05 ± 6.66 | 55.05 ± 6.67 | |
| Gender (male/female) | 14/16 | 20/16 | 19/13 | |
| BMI (kg/m2) | 26.27 ± 2.53 | 27.44 ± 5.25 | 27.44 ± 5.25 | |
| SBP (mmHg) | 128.73 ± 8.35 | 126.24 ± 18.02 | 126.24 ± 13.63 | |
| DBP (mmHg) | 75.07 ± 11.07 | 78.04 ± 17.20 | 77.55 ± 10.58 | |
| TC (mg/dL) | 171.50 ± 19.34 | 178.09 ± 13.86 | 177.27 ± 15.68 | |
| Triglyceride (mg/dL) | 149.45 ± 19.53 | 167.10 ± 24.55 | 158.05 ± 14.37 | |
| FBG (mmol/L) | 5.33 ± 1.64 | 8.04 ± 1.53 | 9.23 ± 1.90* # | |
| HbA1c (%) | 5.54 ± 1.04 | 8.78 ± 2.01 | 7.59 ± 2.33 * | |
| UAE (mg/24 h) | – | 7.25 ± 2.34 | 77.16 ± 30.88* # | |
| eGFR (mL/min) | – | 102.84 ± 10.35 | 67.82 ± 16.56 * # | |
| IL-1β (pg/mL) | – | 7.06 ± 2.99 | 14.16 ± 3.77* # | |
| IL-6 (pg/mL) | – | 7.54 ± 2.26 | 9.60 ± 4.38* # | |
| TNF-α (pg/mL) | – | 8.52 ± 2.99 | 10.32 ± 2.34 * # | |
BMI, body mass index; TC, total cholesterol; FBG fasting blood glucose; HbA1c, glycosylated hemoglobin; UAE, urinary albumin excretion; eGFR, estimated glomerular filtration rate; T2DM, Type 2 diabetes mellitus; DN, diabetic nephropathy
* P < 0.05, compared with Healthy control; ## P < 0.05, compared with T2DM patients