Table 2.
Meta-analysis results for the association between extracellular vesicles and cancer risk.
| No. of studies | Sample size (cases/controls) | x 2 | I 2 (%) | Pooling model | Pooled | OR (95% CI) | P -value | |
|---|---|---|---|---|---|---|---|---|
| Sensitivity | 75 | 6183/2437 | 1689.52 | 95.60 | R | 0.62 | 0.60-0.63 | <0.001 |
| Specificity | 75 | 6183/2437 | 380.38 | 80.50 | R | 0.76 | 0.75-0.78 | <0.001 |
| PLR | 75 | 6183/2437 | 429.81 | 82.80 | R | 3.07 | 2.52-3.75 | <0.001 |
| NLR | 75 | 6183/2437 | 1572.96 | 95.30 | R | 0.34 | 0.28-0.41 | <0.001 |
| DOR | 75 | 6183/2437 | 514.13 | 85.60 | R | 10.98 | 7.53-16.00 | <0.001 |
OR, odds ratio; CI, confidence interval; PLR, positive likelihood ratio; NLR, negative likelihood ratio; DOR, diagnostic odds ratio; x2, chi-squared; R, randomize model.