. Author manuscript; available in PMC: 2021 Oct 29.

Published in final edited form as: Am J Transplant. 2020 Oct 10;21(2):475–483. doi: 10.1111/ajt.16324

Table 3:

Criteria for safe SOT candidates with a prior history of Myeloma (top) or Amyloidosis (bottom).

Criteria for Safe Renal Transplantation in Myeloma

Stringent complete response:

No monoclonal protein in serum or urine by immunofixation,

Normal free light chain ratio

Bone marrow plasma cells <1% by flow or immunohistochemistry

Performance status 0 or 1

FISH at diagnosis fail to demonstrate deletion (17p), t(4;14), t(14;16)

Hematologic remission > 6 months

Criteria for Organ Transplantation in Amyloidosis

Therapeutic response with dFLC of <4 mg/dL

Only one organ involved with amyloidosis

Does not fulfill criteria for symptomatic myeloma

Must be a candidate for stem cell transplantation following organ transplantation

dFLC: difference between involved minus uninvolved serum free light chains