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. 2021 Oct 15;8:727412. doi: 10.3389/fmed.2021.727412

Table 8.

Summary of predictors (analytes) with the highest variable importance in biopsies, assessed both in terms of mean decrease in accuracy and mean decrease in in Gini impurity.

Predictor Mean decrease accuracy Predictor Mean decrease Gini
PD-L2 14.05 PD-L2 8.34
TIM-3 12.12 TIM-3 5.98
IDO 11.61 4-1BB 5.16
4-1BB 7.97 IDO 5.04
LAG-3 7.55 CD80 3.04
CTLA-4 4.73 CTLA-4 2.79
CD80 4.20 LAG-3 2.78
BTLA 3.98 CD28 1.98
CD27 3.87 PD-1 1.91
CD28 3.16 CD27 1.88
GITR 2.53 BTLA 1.67
PD-1 2.29 Age 1.62
HVEM −0.38 GITR 0.95
Age −3.04 HVEM 0.78