Figure 4: Transcriptomic divergence in serological subsets of clinical myositis diagnoses.
(a-b) Median gene expression of patients with the indicated DM-specific autoantibody in A or IMNM-specific autoantibody in B. Circles indicate a region of differential expression. (c) Gene expression signatures – mean log 2 fold change of cluster genes, where the cluster is indicated and highlighted in A or B – for individual patients across the indicated subsets. For more information on individual clusters (numbered), see Online Resource Supplementary Table 2.