TABLE 3.

Stratification of fluconazole-resistant C. albicans isolates by the SQM versus the broth microdilution method

Isolate	MIC determined by:		Ergosterol contentb (reductionc) of cells grown with fluconazole at a concn (μg/ml) of:
	Microdilutiona	SQM	4	16	64
CA23	64	14d	0.7 (65)	0.2 (92)	0 (100)
CA28	≥64	15d	0.5 (66)	0.2 (87)	0 (100)
CA24	64	21d	0.8 (66)	0.7 (62)	0 (100)
CA25	64	51	1.2 (0)	0.7 (42)	0 (100)
CA26	64	51	1.6 (16)	1.2 (37)	0 (100)
CA21	64	52	1.7 (26)	1.3 (44)	0.02 (99)
CA22	64	52	0.9 (40)	0.9 (40)	0.03 (98)
CA27	≥64	61	0.7 (42)	0.3 (75)	0.2 (84)
CA29	≥64	183e	1.2 (33)	1.4 (23)	1.3 (28)
CA30	≥64	190e	0.8 (27)	0.8 (27)	0.8 (27)

^aAfter 48 h of incubation. 

^bExpressed as a percentage of the wet weight of the cell. 

^cPercent reduction in ergosterol content compared with that of control cells grown without fluconazole. 

^dSDD by SQM. 

^eHighly resistant by SQM.