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. 2021 Oct 28;23(10):e28613. doi: 10.2196/28613

Table 5.

The integration of blockchain and emerging technology.

Emerging technology Integrating with blockchain The role of blockchain Reference
AIa Disease diagnosis and prediction, medical image–assisted reading, intelligent devices, new drug research, health management, and gene sequencing Blockchain forms a natural foundation to standardize health data structures for AI training, clinical trials, and regulatory purposes. Blockchain-based AI could thereby accelerate the definition of phenotype-specific outcomes of orphan diseases, improve the representation of racial minorities, and reduce sex-specific inequalities [94,95,98,99]
Cloud computing Supporting communication and sharing data among stakeholders in health care Based on the blockchain and cloud computing, the prediction model of disease evolution will be constructed, which plays a role in the prevention and control of major infectious diseases and tumors involving personal information [82,83,100]
Big data Offering a huge amount of data in real time to reduce health risks and optimize the outcome Big data are stored and shared through a blockchain, thus avoiding the defect that centralized storage is easy to be lost and attacked [77]
Wearable devices Collecting personal data in an intimate and timely manner, the source of health data for telemedicine Blockchain allows continuous individual monitoring, and requires robust, rapid, real-time analysis of physiological signals to avoid the storage of large amounts of data in a centralized system [96]
Internet of Things Supply chain and tracing of drugs, apparatuses, and wearable devices Tracking the source and use of drugs and medical devices in the Internet of Things through blockchain technology to ensure authenticity and reliability [88,100]
5G Improving the speed of medical information sharing The distributed processing of medical data in the 5G environment is carried out by blockchain technology, and access and use can only be achieved by obtaining multiparty permissions [97]

aAI: artificial intelligence.