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. Author manuscript; available in PMC: 2021 Dec 17.
Published in final edited form as: Nat Genet. 2021 Jun 17;53(7):972–981. doi: 10.1038/s41588-021-00879-y

Extended Data Fig. 7. Overlap of significant SNPs between lipid GWAS and lipid-guided PheWAS across cohorts.

Extended Data Fig. 7

UpSet plot indicating overlap of GWAS-significant SNPs (Bonferroni threshold) between each of the four plasma lipids (HDL-C, LDL-C, TC, TG) aggregated across the four considered cohorts (eMERGE, GERA, GLGC, UKB) and lipid-guided PheWAS conducted in eMERGE and UKB, respectively.