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. 2021 Oct 29;398(10316):2093–2100. doi: 10.1016/S0140-6736(21)02249-2

Table 2.

Effectiveness of the third vaccine dose versus two vaccine doses of the BNT162b2 mRNA COVID-19 vaccine

Vaccinated with two doses
Vaccinated with three doses
1 – risk ratio (95% CI) Risk difference per 100 000 individuals (95% CI)
Events Risk per 100 000 individuals Events Risk per 100 000 individuals
Admission to hospital 231 220·8 29 14·4 93% (88–97) 206·4 (146·1–275·1)
Severe disease 157 158·9 17 12·9 92% (82–97) 145·9 (93·1–207·7)
Death 44 31·9 7 6·1 81% (59–97) 25·8 (13·0–38·5)

Estimates were obtained using the Kaplan-Meier estimator starting from day 7 after receipt of the third dose, in those who received it.