Table 6.
Adjusted healthcare costs of MBC progression and MBC progression free patients.
Cost ratios | Total costs | 95% CI | OP costs | 95% CI | OP drug costs | 95% CI | IP costs | 95% CI | IP drug costs | 95% CI | ER costs | 95% CI |
Intercept | 2,479 | 1,885.40 | 3,261.91 | 808.11 | 623.09 | 1048.06 | 179.72∗ | 121.58 | 265.68 | 3,988.32∗ | 2,806.56 | 5,667.68 | 1,027.02 | 539.15 | 1,956.33 | 193.74∗ | 129.60 | 289.62 |
Group | ||||||||||||
BCF | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||||||
MBC | ||||||||||||
Progression | 16.28∗ | 13.76–19.28 | 21.12∗ | 18.00–24.77 | 65.35∗ | 51.6–82.70 | 1.94∗ | 1.58–2.37 | 5.03∗ | 3.46–7.31 | 2.64∗ | 2.13–3.27 |
Progression free | 2.71∗ | 2.54–2.88 | 2.88∗ | 2.72–3.06 | 4.31∗ | 3.95–4.71 | 1.51∗ | 1.34–1.70 | 1.61∗ | 1.30–2.00 | 1.47∗ | 1.33–1.62 |
BC | 8.87∗ | 8.53–9.22 | 8.95∗ | 8.63–9.29 | 15.13∗ | 14.3–16.01 | 1.69∗ | 1.58–1.81 | 4.47∗ | 3.90–5.13 | 1.55∗ | 1.46–1.64 |
Age | ||||||||||||
20–30 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||||||
31–40 | 1.10 | 0.90–1.34 | 1.07 | 0.89–1.29 | 1.12 | 0.85–1.48 | 1.53∗ | 1.19–1.95 | 1.77∗ | 1.12–2.79 | 1.31 | 0.98–1.77 |
41–50 | 1.11 | 0.91–1.34 | 1.18 | 0.98–1.41 | 1.21 | 0.93–1.59 | 1.30∗ | 1.02–1.65 | 1.37 | 0.88–2.13 | 1.32 | 0.98–1.76 |
51–60 | 1.31∗ | 1.08–1.59 | 1.43∗ | 1.19–1.72 | 1.59∗ | 1.21–2.09 | 1.26 | 0.99–1.61 | 1.27 | 0.82–1.98 | 1.44∗ | 1.07–1.92 |
61–70 | 1.62∗ | 1.33–1.97 | 1.71∗ | 1.42–2.06 | 2.04∗ | 1.55–2.69 | 1.36∗ | 1.06–1.73 | 1.14 | 0.72–1.79 | 2.03∗ | 1.51–2.72 |
71–80 | 1.99∗ | 1.62–2.45 | 1.71∗ | 1.41–2.08 | 2.07∗ | 1.55–2.76 | 1.86∗ | 1.44–2.41 | 1.55 | 0.96–2.49 | 2.39∗ | 1.76–3.25 |
> = 81 | 2.59∗ | 2.01–3.34 | 1.87∗ | 1.47–2.37 | 2.03∗ | 1.42–2.90 | 2.16∗ | 1.58–2.94 | 1.18 | 0.67–2.10 | 3.48∗ | 2.45–4.95 |
Residential area | ||||||||||||
Northern | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||||||
Central | 0.44∗ | 0.36–0.54 | 0.90 | 0.74–1.08 | 0.88 | 0.67–1.17 | 0.46∗ | 0.35–0.59 | 0.25∗ | 0.16–0.41 | 0.47∗ | 0.35–0.62 |
Southern | 0.49∗ | 0.40–0.60 | 0.99 | 0.82–1.19 | 0.96 | 0.72–1.27 | 0.47∗ | 0.36–0.61 | 0.22∗ | 0.13–0.35 | 0.52∗ | 0.39–0.69 |
Eastern | 0.51∗ | 0.42–0.63 | 1.00 | 0.83–1.21 | 0.97 | 0.73–1.30 | 0.54∗ | 0.41–0.70 | 0.29∗ | 0.18–0.48 | 0.40∗ | 0.30–0.54 |
CCI score | ||||||||||||
CCI = 0 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||||||
CCI = 1 | 1.97∗ | 1.86–2.08 | 1.93∗ | 1.83–2.04 | 2.39∗ | 2.21–2.59 | 1.33∗ | 1.24–1.43 | 1.51∗ | 1.32–1.73 | 1.45∗ | 1.34–1.57 |
CCI≥2 | 3.09∗ | 2.81–3.39 | 2.29∗ | 2.09–2.50 | 2.99∗ | 2.62–3.41 | 2.28∗ | 2.02–2.57 | 3.43∗ | 2.73–4.30 | 2.29∗ | 2.01–2.60 |