Skip to main content
. 2021 Oct 22;2021:4409212. doi: 10.1155/2021/4409212

Table 3.

Correlation between molecular expression of oxidative stress genes with celluar hormones and mood scores in older adults with neurodepression disorders (n =40).

Variables m-RNA expression of oxidative stress genes in neurodepressed adults (n =40)
NO iNOS SOD2 CAT
Rs P Rs P Rs P Rs P
Cortisol 0.75 0.01 0.35 0.01 -0.43 0.001 -0.31 0.01
Serotonin -0.28 0.01 -0.18 0.01 0.15 0.001 0.21 0.01
TMScore 0.56 0.01 0.39 0.01 0.38 0.001 0.46 0.001
Domains of POMScores
Depression 0.24 0.01 0.14 0.01 0.22 0.01 0.23 0.01
Anger 0.35 0.01 0.23 0.01 0.31 0.01 0.38 0.01
Fatigue 0.13 0.01 0.31 0.01 0.38 0.01 0.34 0.01
Vigour 0.58 0.01 0.14 0.01 0.53 0.01 0.36 0.01
Tension 0.49 0.01 0.18 0.01 0.29 0.01 0.58 0.01

Spearman's rho (rs) of miRNA relative expression levels vs. cellular oxidative stress genes, hormones activity, and mood score, 2-tailed significance (P), and number of subjects are presented. Correlations observed included hormonal markers and mood score frequency based on expression profiles of cellular oxidative stress genes. Nitric oxide (NO); endothelial nitric oxide synthase (iNOS); superoxide dismutase enzyme (SOD2); catalase enzyme (CAT); total mood score (TMscore); Profile of mood states (POMS).