Table 4.

Correlation studies between microRNA expression, celluar oxidative stress, hormones activity, and mood scores in older adults with neurodepression disorders (n =40).

Variables	MicroRNAs expression in neurodepressed adults (n =40)
	miR-124		miR-34a-5p		miR-135		miR-451a
	Rs	P	Rs	P	Rs	P	Rs	P
NO	0.36	0.01	0.42	0.01	0.32	0.001	0.52	0.01
iNOs	0.32	0.001	0.63	0.01	0.39	0.001	0.46	0.01
SOD2	-0.21	0.01	-0.25	0.01	-0.37	0.001	-0.47	0.01
CAT	-0.51	0.01	-0.37	0.01	-0.48	0.001	-0.31	0.01
Cortisol	0.48	0.01	0.28	0.01	0.38	0.001	0.67	0.01
Serotonin	-0.21	0.01	-0.21	0.01	-0.41	0.001	-0.51	0.01
TMscore	0.37	0.004	0.31	0.01	0.75	0.001	0.69	0.01

Spearman's rho (rs) of miRNA relative expression levels vs. cellular oxidative stress, hormones activity, and mood score, 2-tailed significance (P), and number of subjects are presented. Correlations observed included celluar oxidative and hormonal markers, and mood score frequency based on miRNAs profiling. Nitric oxide (NO); endothelial nitric oxide synthase (iNOS); superoxide dismutase enzyme (SOD2); catalase enzyme (CAT); total mood score (TMscore).