Table 2.
Baseline demographic and clinical characteristics according to in-hospital RASI therapy.
| OVERALL POPULATION (N = 3812) |
YEAR 2019 (N = 2038) |
YEAR 2020 (N = 1774) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| RASI (n = 2049) | No RASI (n = 1763) | P value | RASI (n = 1034) | No RASI (n = 1004) | P value | RASI (n = 1015) | No RASI (n = 759) | P value | |
| Age (median, IQR) | |||||||||
| Age > 75 year – n. (%) | 434 (21.2) | 446 (25.3) | 0.003 | 230 (22.2) | 260 (25.9) | 0.054 | 204 (20.1) | 186 (24.5) | 0.027 |
| Male gender – n. (%) | 1504 (73.4) | 1182 (67.0) | <0.004 | 773 (74.8) | 685 (68.2) | 0.001 | 731 (72.0) | 497 (65.5) | 0.003 |
| Hypertension- n (%) | 1509 (73.6) | 1268 (71.9) | 0.233 | 742 (71.8) | 733 (73.0) | 0.529 | 767 (75.6) | 535 (70.5) | 0.017 |
| Hypercholesterolemia - n (%) | 1129 (55.1) | 849 (48.2) | <0.001 | 550 (53.2) | 486 (48.4) | 0.031 | 579 (57.0) | 363 (47.8) | <0.001 |
| Active Smoker – n (%) | 1026 (50.1) | 768 (43.6) | <0.001 | 505 (48.8) | 436 (43.4) | 0.014 | 521 (51.3) | 332 (43.7) | 0.002 |
| Family History of CAD - n (%) | 416 (20.3) | 248 (14.1) | <0.001 | 223 (21.6) | 144 (14.3) | <0.001 | 193 (19.0) | 104 (13.7) | 0.003 |
| Previous STEMI- n (%) | 296 (14.4) | 200 (11.3) | 0.005 | 145 (14.0) | 108 (10.8) | 0.025 | 151 (14.9) | 92 (12.1) | 0.095 |
| Previous PCI – n (%) | 408 (19.9) | 297 (16.8) | 0.015 | 189 (18.3) | 166 (16.5) | 0.299 | 219 (21.6) | 131 (17.3) | 0.024 |
| Previous CABG - n (%) | 67 (3.3) | 52 (2.9) | 0.571 | 37 (3.6) | 27 (2.7) | 0.250 | 30 (3.0) | 25 (3.3) | 0.684 |
| Referral to Primary PCI Hospital | |||||||||
| Ambulance (from community) – n (%) |
1011 (49.3) | 659 (37.4) | <0.001 | 508 (49.1) | 379 (37.7) | <0.001 | 503 (49.6) | 280 (36.9) | <0.001 |
| Time delays | |||||||||
| Ischemia time, median [25 - 75th] | |||||||||
| Total Ischemia time > 12 h – n (%) | 267 (13.0) | 248 (14.1) | 0.351 | 124 (12.0) | 122 (12.2) | 0.912 | 143 (14.1) | 126 (16.6) | 0.144 |
| Door-to-balloon time, median [25 - 75th] | |||||||||
| Door-to-balloon time > 30 min - n (%) |
1227 (59.9) | 1167 (66.2) | <0.001 | 611 (59.1) | 664 (66.1) | 0.001 | 616 (60.7) | 503 (66.3) | 0.016 |
| Clinical Presentation | |||||||||
| Anterior STEMI– n (%) | 978 (47.7) | 854 (48.4) | 0.662 | 501 (48.5) | 477 (47.5) | 0.670 | 477 (47.0) | 377 (49.7) | 0.264 |
| Out-of-hospital cardiac arrest – n (%) | 69 (3.4) | 100 (5.7) | 0.001 | 32 (3.1) | 58 (5.8) | 0.003 | 37 (3.6) | 42 (5.5) | 0.056 |
| Cardiogenic shock– n (%) | 123 (6.0) | 226 (12.8) | <0.001 | 53 (5.1) | 126 (12.5) | <0.001 | 70 (6.9) | 100 (13.2) | <0.001 |
| Rescue PCI for failed thrombolysis – n (%) | 143 (7.0) | 161 (9.1) | 0.014 | 79 (7.6) | 84 (8.4) | 0.546 | 64 (6.3) | 77 (10.1) | 0.003 |
*Mann-Whitney test.
CAD = Coronary Artery Disease; STEMI = ST-segment Elevation Myocardial Infarction; PCI = Percutaneous Coronary Intervention; CABG = Coronary Artery Bypass Graft;.