Table 11.

All-grade adverse events of urinary system origin in cancer patients treated with ICI [71, 74, 76, 77, 79–81]

System	Organ	Symptoms	Abnormalities in diagnostic test results	Suspected pathology
Urinary system	Kidney	Hematuria Oliguria Hypertension Fever Eosinophilia Skin rash Weakness Loss of appetite Nausea/vomiting Oliguria	Creatine increase Eosinophilia Disorders in serum electrocytes (hyperkaliemia, mild hyponatremia) Gasometry (acidosis) Urinalysis (proteinuria, abnormal urine sediment) USG Renal biopsy (inflammatory infiltrates, involving cortex more than medulla, interstitial edema, picture generated for gel-induced interstitial nephritis, features of acute tubulointerstitial nephritis)	Nephritis, acute kidney injury (AKI)
				Acute interstitial nephritis (AIN)