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. 2021 Jul 8;40(3):949–982. doi: 10.1007/s10555-021-09976-0

Table 8.

Incidence of all-grade respiratory adverse events in cancer patients treated with ICI [66, 7479, 101]

Drugs/irAE Anti-PD-1/PD-L1 Anti-CTLA-4 Combined treatment
Pneumonitis

0.4% [76]

1–5% [74]

1.4–2.0% [78]

2.7% [79]

3.8% [75]

0.4–2.2% [76]

0.7% [78]

<1% [79]

7% [77]

2.1% [76]

3–7% [74]

6.5% [77]

7.5–10.5% [78]

9.6% [75]

10% [79]

Cough 4% [101] NR 7.5% [101]
Dyspnea

3.3% [101]

4.5% [66]

4.2% [66]

9.4% [101]

10.2% [66]

NR not reported