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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Adv Drug Deliv Rev. 2021 Sep 13;178:113971. doi: 10.1016/j.addr.2021.113971

Fig.1.

Fig.1.

Maintenance of Immune Homeostasis. (A) When inflammatory cues (i.e., effector cells, mature dendritic cells, inflammatory cytokines) are balanced by anti-inflammatory cues (i.e., regulatory T cells, immature dendritic cells, anti-inflammatory cytokines, etc.), the immune system is in a state of immunological equilibrium. (B) If there is a greater ratio of anti-inflammatory to inflammatory signals, diseases such as cancer can develop and propagate. (C) If there is a greater ratio of inflammatory to anti-inflammatory signals, conditions such as autoimmune diseases and transplant rejection can develop and propagate.