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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Adv Drug Deliv Rev. 2021 Sep 13;178:113971. doi: 10.1016/j.addr.2021.113971

Table 1.

Commonly used synthetic polymers for the development of local delivery strategies to restore immune homeostasis from inflammation.

Polymer Structure Local Delivery Strategies Ref(s)
Polyesters
 Poly (caprolactone) (PCL) graphic file with name nihms-1742581-t0002.jpg PEG-PCL-PEG MPs [64]
 Poly (lactic-co-glycolic acid) (PLGA) graphic file with name nihms-1742581-t0003.jpg PLGA MPs [59,65,66]
Polyethers
 Poly (ethylene glycol) (PEG) graphic file with name nihms-1742581-t0004.jpg PEG-PCL-PEG MPs [46,59,67,68]
 Poly (ethylene glycol) methacrylate (PEGMA) graphic file with name nihms-1742581-t0005.jpg PEGMA hydrogel [59,70,74]
Poly (N-acrylamides)
 Poly (N-isopropylacrylamide) (pNIPAM) graphic file with name nihms-1742581-t0006.jpg PLGA MPs/pNIPPAM hydrogel; pNIPAm-chitosan-hylauronic acid hydrogel [59,76,79]
Poloxamers
 Pluronic® F127 (F127) graphic file with name nihms-1742581-t0007.jpg F127/F68 hydrogel [33,37,80]
 Pluronic® F68 (F68) graphic file with name nihms-1742581-t0008.jpg F127/F68 hydrogel [33,37,80]
Poly (amino acids)
 Poly (lysine) (Lys) graphic file with name nihms-1742581-t0009.jpg P-Lys-Ala-PLX hydrogel [75,83]
 Poly (alanine) (Ala) graphic file with name nihms-1742581-t0010.jpg P-Lys-Ala-PLX hydrogel [75,83]