Table 3.
Diagnostic power of AFP to discriminate patients with HCC from patients with cirrhosis in different three staging systems
Classification | AUC | Sens% | Spe% | PPV% | NPV% | AC% |
---|---|---|---|---|---|---|
Number of nodules (n, %) | ||||||
Single (67, 43.2%) | 0.71 | 22 | 100 | 100 | 53 | 58 |
Multiple (88, 56.8) | 0.74 | 31 | 100 | 100 | 52 | 60 |
Macrovascular invasion (n, %) | ||||||
Absent (141, 91%) | 0.74 | 25 | 100 | 100 | 38 | 48 |
Present (14, 9%) | 0.65 | 50 | 100 | 100 | 90 | 91 |
Size of nodules (n, %) | ||||||
<2 (48, 31%) | 0.72 | 13 | 100 | 100 | 63 | 65 |
>2 (107, 69%) | 0.75 | 33 | 100 | 100 | 49 | 59 |
BCLC stage (n, %) | ||||||
0-A (109, 70.3%) | 0.71 | 19 | 100 | 100 | 41 | 48 |
B (46, 29.7) | 0.8 | 52 | 100 | 100 | 75 | 80 |
CLIP stage (n, %) | ||||||
0-1 (122, 79%) | 0.69 | 17 | 100 | 100 | 39 | 45 |
2-3 (33, 21%) | 0.88 | 63 | 100 | 100 | 82 | 86 |
Okuda stage (n, %) | ||||||
Stage I (117, 75.5%) | 0.67 | 23 | 100 | 100 | 41 | 50 |
Stage II (38, 24.5%) | 0.89 | 39 | 100 | 100 | 70 | 75 |