Table 2.
P values for the macrophages after 24 and 48 h at different concentrations of the formulations. Values are statistically significant at P < 0.05 as calculated by ANOVA test
| C/ μg mL | aART vs. NLC | ART vs.b NLC-ART | ART vs.c AMB | NLC versus NLC-ART | NLC versus AMB | NLC-ART versus AMB | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | |
| 2.5 | 0.9490 | 0.8561 | 0.9490 | 0.9208 | 0.0384 | 0.0675 | 0.9999 | 0.9985 | 0.0093 | 0.0088 | 0.0093 | 0.0138 |
| 5 | 0.4310 | 0.5986 | 0.6817 | 0.7556 | 0.0012 | < 0.0001 | 0.9766 | 0.9938 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| 10 | 0.0652 | 0.0675 | 0.3294 | 0.7556 | < 0.0001 | < 0.0001 | 0.8367 | 0.9153 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| 25 | 0.0004 | < 0.0001 | 0.0163 | < 0.0001 | < 0.0001 | < 0.0001 | 0.6129 | 0.9862 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| 50 | < 0.0001 | < 0.0001 | 0.0103 | < 0.0001 | < 0.0001 | < 0.0001 | 0.3018 | 0.5179 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| 100 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | 0.2132 | 0.0285 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
aArtemether versus Nanostructured lipid carrier
bNanostructured lipid carrier loaded with Artemether
cAmphotericin B