Table 3.
IC50 (μg/ml), CC50 (μg/ml) and selectivity index (SI) (μg/ml) for promastigotes and amastigotes
| Time/h | ART | NLC | NLC-ART | AMB |
|---|---|---|---|---|
| Promastigote IC50* | ||||
| 24 | 57.73 | 2855 | 31.52 | 8.71 |
| 48 | 37.12 | 1952 | 16.43 | 5.631 |
| CC50** | ||||
| 48 | 363.4 | 4853 | 788.7 | 86.51 |
| Amastigote IC50 | ||||
| 24 | 45.2 | 1151 | 27.95 | 8.43 |
| 48 | 32.1 | 1724 | 15.42 | 7.36 |
| SI*** | ||||
| 48 | 9.789871 | 2.486168 | 48.00365 | 15.36317 |
*Concentration of particles which has 50% inhibitory in promastigote forms
**Concentration of particles which has 50% cytotoxicity in macrophages
***Selectivity index