Table 2.
Variables (Mean ± SEM) | ||||
---|---|---|---|---|
Drug doses (mg/kg) | Weight (g) | ALT (U/L) | AST (U/L) | ALP (U/L) |
10 | 26 ± 6.22 | 77.60 ± 3.64 | 117.14 ± 3.36 | 159 ± 3.96 |
20 | 27.31 ± 0.64 | 69 ± 3.13 | 130 ± 14.29 | 151 ± 15.22 |
40 | 26.62 ± 0.24 | 71.64 ± 2.34 | 126.61 ± 13.27 | 157.32 ± 7.11 |
50 | 27.12 ± 0.69 | 70.31 ± 7.23 | 145.60 ± 12.75 | 158.61 ± 11.90 |
80 | 26.31 ± 0.73 | 81 ± 7.48a | 159 ± 17.21a | 173 ± 5.17 |
100 | 27 ± 0.37 | 79 ± 7.81a | 126.64 ± 12.56 | 172 ± 7.22 |
200 | 27.62 ± 0.68 | 99.31 ± 4.12a | 168.31 ± 12.37a | 209.64 ± 12a |
400 | 24 ± 0.44 | 267 ± 11.46a | 301 ± 63a | 323.34 ± 13.22a |
Positive control | 26.31 ± 0.53 | 99 ± 5.65a | 166.34 ± 20a | 189 ± 19.10a |
Negative control | 27.32 ± 0.61 | 67.32 ± 1.88 | 122 ± 8.94 | 155 ± 13.14 |
"a" indicate significant statistical differences between negative control and experimental groups (p < 0.05)