Table 4.
Effect of rumen-protected glucose (RPG) on expression of genes associated with TLR pathway and barrier function in the cecal mucosa of transition dairy cows1.
Gene | CON | RPG | SEM | P-value |
---|---|---|---|---|
TLR2 | 1.19 | 1.35 | 0.18 | 0.623 |
TLR4 | 1.05 | 0.39 | 0.14 | 0.016 |
TLR6 | 1.10 | 0.44 | 0.17 | 0.027 |
TLR7 | 1.03 | 0.20 | 0.16 | 0.019 |
TOLLIP | 1.12 | 1.51 | 0.13 | 0.140 |
IFNG | 1.05 | 0.30 | 0.16 | 0.016 |
CD45 | 1.06 | 0.76 | 0.12 | 0.556 |
IL6 | 1.13 | 0.22 | 0.20 | 0.032 |
IL22 | 1.12 | 0.25 | 0.19 | 0.032 |
IL17F | 1.02 | 0.34 | 0.14 | 0.019 |
IL17A | 1.06 | 0.20 | 0.18 | 0.016 |
Occludin | 1.03 | 2.56 | 0.39 | 0.032 |
Claudin1 | 1.07 | 0.79 | 0.11 | 0.413 |
Claudin4 | 1.11 | 1.54 | 0.21 | 0.286 |
TPJ1 | 1.15 | 1.29 | 0.19 | 0.556 |
TLR = Toll-like receptor; TOLLIP = toll interacting protein; IFNG = immune interferon gamma; CD45 = protein tyrosine phosphatase receptor type C; IL = interleukin; TPJ1 = tight junction protein 1.
CON: the control group which fed a basal diet add with coating fat; RPG: the RPG group which fed a basal diet add with RPG.