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. 2021 Oct 19;7(4):1152–1161. doi: 10.1016/j.aninu.2021.10.001

Table 7.

Summary of the metabolites that changed significantly in the livers of growing heifers fed a Lys-adequate diet through HILIC-MS analysis.

Metabolites1 ID2 Formula VIP P-value FC3 Direction4
L-Histidine HMDB00177 C6H9N3O2 1.41 0.044 0.87 ↓
L-Leucine HMDB00687 C6H13NO2 1.39 0.047 0.81 ↓
L-Aspartic acid HMDB00191 C4H7NO4 1.39 0.018 0.78 ↓

HILIC-MS = hydrophilic interaction liquid chromatography-mass spectrometry; VIP = variable important in projection; FC = fold change.

1

The different metabolites were filtered using significance estimate of P < 0.05 and VIP > 1.0 (n = 5). LD group: growing heifers fed a Lys-deficient diet; LA group: growing heifers fed a Lys-adequate diet.

2

Compound ID of metabolites in human metabolome database.

3

Fold change indicates the relative amounts of LA group compared with LD group.

4

‘↓’ indicates the metabolite in LA group was decreased when compared with LD group.