Table 5.
Heritability and Pairwise Genetic Correlation Between Traits
| Trait 1 | Trait 2 | Heritability of Trait 1 ( ± SE) | Genetic Correlation (rg ± SE) | P |
|---|---|---|---|---|
| Corneal curvature (UKB; 22k) | Eye size (UKB; 22k) | 0.42 ± 0.04 | 0.96 ± 0.04 | 5.71e-119 |
| Height (UKB; 22k) | Eye size (UKB; 22k) | 0.51 ± 0.05 | 0.23 ± 0.05 | 3.71e-07 |
| Refractive error (UKB; 22k) | Eye size (UKB; 22k) | 0.30 ± 0.03 | 0.00 ± 0.06 | 9.53e-01 |
| Refractive error (CREAM+23andMe; 160k) | Eye size (UKB; 22k) | 0.19 ± 0.01 | −0.03 ± 0.05 | 5.13e-01 |
| Eye size (UKB; 22k) | — | 0.42 ± 0.04 | — | — |
P values are for a test of the null hypothesis that the genetic correlation is different from zero. UKB, UK Biobank; 22k, sample size of 22,180; 160k, sample size of 160,420.