Table 1.
Most widely used potentially QT-prolonging drugs that should be avoided in patients with long QT and their associated risk.66
| Risk | AAD | AB/AFA/AM | AP/AD | Anesthetic | Other |
|---|---|---|---|---|---|
| Known | Amiodarone Dronedarone Disopyramide Dofetilide Flecainide Ibutilide Procainamide Quinidine Sotalol |
Azithromycin Ciprofloxacin Clarithromycin Erythromycin Fluconazole Gatifloxacin Levofloxacin Moxifloxacin Roxithromycin Chloroquine Hydroxychloroquine |
Chlorpromazine Citalopram |
Propofol Sevoflurane |
Cocaine Methadone Domperidone Levosulpiride Ondansetron Other antineoplastic drugs |
| Possible | Norfloxacin Ofloxacin |
Lithium Venlafaxine Aripiprazole Clozapine |
Tramadol | Alfuzosin Nicardipine Oxytocin Other antineoplastic drugs |
|
| Conditional | Ivabradine Propafenone Ranolazine |
Piperacillin/tazobactam Amphotericin B Ketoconazole Metronidazole Voriconazole |
Amisulpride Amitriptyline Fluoxetine Olanzapine Paroxetine Quetiapine Risperidone Sertraline Trazodone |
Hydrochlorothiazide Torasemide Amantadine Indapamide Furosemide Loperamide Metolazone Metoclopramide Omeprazole Lansoprazole Pantoprazole Esomeprazole |
|
| Special | Drugs used for the treatment of asthma, –ADHD, or nasal congestion | ||||
Abbreviations: AAD, antiarrhythmic drugs; AB, antibiotics; AD, antidepressants; ADHD, attention-deficit hyperactivity disorder; AFA, antifungal agents; AM, antimalarials; AP, antipsychotics.