Standardized estimates for the associations between negative life events, cingulo-opercular (CO) network-amygdala connectivity, and psychopathology. A) Model with CO-left amygdala connectivity, B) Model with CO-right amygdala connectivity. All models controlled for the effects of age, sex, and baseline CO-amygdala connectivity, and included main and interaction effects of parental acceptance on connectivity (not pictured for clarity). Non-significant paths illustrated by dashed lines. * p < .05, ** p < .01, *** p < .001.