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. 2021 Oct 30;16:458. doi: 10.1186/s13023-021-02082-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Sympathetic Skin response in upper and lower limbs. A Normal symmetrical sympathetic skin response (SSR) in upper limbs in individual -30- after electrical stimulus in left hand, recorded simultaneously in both hands. Upper curves refer to the left hand, lower curves refer to the right hand. B Pathological asymmetrical in amplitude and morphology SSR in upper limbs in individual -23- after electrical stimulus in right hand, recorded simultaneously in both hands. Upper curves refer to the left hand, lower curves refer to the right hand. C Normal symmetrical normal SSR in lower limbs in individual -30- after electrical stimulus in left foot, recorded simultaneously in both feet. Upper curves refer to the left foot, lower curves refer to the right foot. D Pathological symmetrical in amplitude SSR in lower limbs in individual -40- after electrical stimulus in right foot, recorded simultaneously in both feet. Upper curves refer to the left foot, lower curves refer to the right foot