Table 2.
Results of voxel-based regression analyses between neuroimaging parameters and years of education
| Region | Number of voxels | t-score | MNI coordinates | ||
|---|---|---|---|---|---|
| x | y | z | |||
| Negative correlations between years of education and GMV | |||||
| dorsal anterior cingulate cortex | 291 | −5.25 | 0 | 20 | 33 |
| Negative correlations between years of education and ReHo | |||||
| left anterior part of inferior temporal cortex | 65 | −6 | −57 | − 12 | −33 |
| left posterior part of inferior temporal cortex | 59 | −4.69 | −51 | −30 | −21 |
| Negative correlations between years of education and left aITC rsFC | |||||
| right angular gyrus | 32 | −4.79 | 45 | −66 | 42 |
| left mid frontal cortex | 27 | −5.57 | −39 | 15 | 57 |
| right superior frontal cortex | 16 | −4.95 | 24 | 27 | 54 |
Structural MR (GMV): Adjusted for age, sex, MMSE, and TIV
Resting-state fMRI (ReHo and rsFC): Adjusted for age, sex, MMSE, and head motion parameters
Coordinates (x,y,z) are given in MNI standard space. All regions listed are statistically significant at p<0.05 level (FDR corrected)
Abbreviations: GMV gray matter volume; ReHo Regional Homogeneity; rsFC resting-state functional connectivity; MNI Montreal Neurological Institute; aITC anterior part of inferior temporal cortex; MMSE Mini-Mental State Examination; TIV total intracranial volume