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. 2021 Oct 30;21:423. doi: 10.1186/s12883-021-02445-9

Table 4.

Correlations between ROI-based neuroimaging variables and clinical cognitive function scores in AD group

Cognitive system Episodic memory Semantic memory Working memory
r p r p r p
aGMV of dACC 0.334 0.015* 0.453 0.001** 0.205 0.141
bReHo of left aITC 0.172 0.217 0.049 0.728 0.021 0.884
bReHo of left pITC 0.391 0.004** 0.2 0.151 0.102 0.466
Left aITC rsFCb
 right angular gyrus 0.312 0.023* 0.082 0.562 0.089 0.525
 Left middle frontal cortex 0.338 0.013* 0.277 0.045* 0.084 0.552
 right superior frontal cortex 0.108 0.44 −0.035 0.805 −0.128 0.36

The relationship between neuroimaging variables and clinical cognitive function scores were assessed by using Pearson correlation analysis

aAdjusted for age, sex, education, and TIV

bAdjusted for age, sex, education, and head motion parameters

P< 0.05*, P< 0.01**, P< 0.001***

Abbreviations: AD Alzheimer’s disease; GMV gray matter volume; ReHo Regional Homogeneity; rsFC resting-state functional connectivity; dACC dorsal anterior cingulate cortex; aITC anterior part of inferior temporal cortex; pITC posterior part of inferior temporal cortex; TIV total intracranial volume; ROI region of interest