Table 1.
Univariate analysis of baseline characteristics and laboratory indicators of patients with acute cerebral infarction
| Clinical features and laboratory indicators | Good prognosis (n = 630) | Poor prognosis (n = 207) | Non-parametric test(Z or X2 )value | P value |
|---|---|---|---|---|
| Age (years), M(QR) | 64 (21) | 74 (16) | − 8.130 | 0.000 |
| Admission NIHSS, M(QR) | 2 (4) | 8 (9) | − 13.315 | 0.000 |
| Barthel index, M(QR) | 90 (30) | 35 (50) | − 14.781 | 0.000 |
| Hemoglobin (g/L), M(QR) | 141 (22) | 136 (27) | − 3.972 | 0.000 |
| Triglycerides (mmol/L), M(QR) | 1.40 (1.04) | 1.19 (1.09) | − 2.417 | 0.016 |
| Cholesterol (mmol/L), M(QR) | 4.56 (1.34) | 4.34 (1.83) | − 1.652 | 0.098 |
| Low-density lipoprotein (mmol/L), M(QR) | 2.59 (1.04) | 2.45 (1.42) | − 1.933 | 0.053 |
| High density lipoprotein (mmol/L), M(QR) | 0.75 (0.24) | 0.75 (0.28) | − 0.311 | 0.756 |
| Blood sugar (mmol/L), M(QR) | 6.58 (3.46) | 7.30 (4.28) | − 3.150 | 0.002 |
| Creatinine (umol/L), M(QR) | 71.10 (23.28) | 73.20 (27.80) | − 2.182 | 0.029 |
| Urea nitrogen (umol/L), M(QR) | 5.30 (2.23) | 6.00 (3.10) | − 4.174 | 0.000 |
| Gender, n(%) | 5.034 | 0.025 | ||
| Female | 182 (28.9%) | 77 (37.2%) | ||
| Male | 448 (71.1%) | 130 (62.8%) | ||
| History | ||||
| Diabetes, n(%) | 7.394 | 0.007 | ||
| No | 436 (69.2%) | 122 (58.9%) | ||
| Yes | 194 (30.8%) | 85 (41.1%) | ||
| Hypertension, n(%) | 3.615 | 0.057 | ||
| No | 225 (35.7%) | 59 (28.5%) | ||
| Yes | 405 (64.3%) | 148 (71.5%) | ||
| Hyperlipidemia, n(%) | 0.260 | 0.610 | ||
| No | 527 (83.7%) | 170 (82.1%) | ||
| Yes | 103 (16.3%) | 37 (17.9%) | ||
| Smoking, n(%) | 10.294 | 0.016 | ||
| No smoking | 316 (50.2%) | 121 (58.5%) | ||
| Quit smoking | 67 (10.6%) | 26 (12.5%) | ||
| Still smoking | 240 (38.1%) | 55 (26.6%) | ||
| Unknown | 71 (1.1%) | 5 (2.4%) | ||
| Drinking, n(%) | 15.959 | 0.014 | ||
| No drinking | 407 (64.6%) | 159 (76.8%) | ||
| Drink moderately | 146 (23.2%) | 28 (13.5%) | ||
| Moderate drinking | 33(5.2%) | 6 (2.9%) | ||
| Heavy drinking | 10(1.6%) | 1 (0.5%) | ||
| Unknown alcohol consumption | 12(1.9%) | 2 (1.0%) | ||
| Quit alcohol | 19 (3.0%) | 9 (4.3%) | ||
| Unknown | 3 (0.5%) | 2 (1.0%) | ||
| Cerebral Infarction, n(%) | 39.796 | 0.000 | ||
| No | 480 (76.2%) | 110 (53.1%) | ||
| Yes | 150 (23.8) | 97 (46.9%) | ||
| Cerebral hemorrhage, n(%) | 9.937 | 0.002 | ||
| No | 616 (97.8%) | 193 (93.2%) | ||
| Yes | 14 (2.2%) | 14 (6.8%) | ||
| TIA, n(%) | 3.256 | 0.071 | ||
| No | 623 (98.9%) | 201 (97.1%) | ||
| Yes | 7 (1.1%) | 6 (2.9%) | ||
| Heart failure, n(%) | 4.176 | 0.041 | ||
| No | 624 (99.0%) | 201 (97.1%) | ||
| Yes | 6 (1.0%) | 6 (2.9%) | ||
| Coronary Heart Disease, n(%) | 6.182 | 0.013 | ||
| No | 529 (84.0%) | 158 (76.3%) | ||
| Yes | 101 (16.0%) | 49 (23.7%) | ||
| Atrial fibrillation, n(%) | 12.796 | 0.000 | ||
| No | 589 (93.5%) | 177 (85.5%) | ||
| Yes | 41 (6.5%) | 30 (14.5%) | ||
| Tumor, n(%) | 10.673 | 0.001 | ||
| No | 615 (97.6%) | 192 (92.8%) | ||
| Yes | 15 (2.4%) | 15 (7.2%) | ||
| MRS at admission, n(%) | 263.515 | 0.000 | ||
| 0 | 13 (2.1%) | 2 (1.0%) | ||
| 1 | 175 (27.8%) | 6 (2.9%) | ||
| 2 | 192 (30.5%) | 24 (11.6%) | ||
| 3 | 154 (24.4%) | 36 (17.4%) | ||
| 4 | 87 (13.8%) | 77 (37.2%) | ||
| 5 | 9 (1.4%) | 62 (30.0%) | ||
| Length of hospital stay, n(%) | 124.628 | 0.000 | ||
| < 2 weeks | 402 (63.8%) | 67 (32.4%) | ||
| ≥ 2 weeks and < 4 weeks | 214 (34.0%) | 92 (44.4%) | ||
| ≥ 4 weeks | 14 (2.2%) | 48 (23.2%) | ||
| TOAST type, n(%) | 48.677 | 0.000 | ||
| Atherosclerotic stroke | 333 (52.9%) | 104 (50.2%) | ||
| Cardiogenic embolism | 20 (3.2%) | 27 (13.0%) | ||
| Arteriole occlusive stroke | 133 (21.1%) | 14 (6.8%) | ||
| Uncertain cause | 144 (22.8%) | 62 (30.0%) | ||
| Circulatory system, n(%) | 21.415 | 0.000 | ||
| Anterior circulatory system | 387 (61.4%) | 151 (72.9%) | ||
| Posterior circulatory system | 207 (32.9%) | 35 (16.9%) | ||
| Anterior and posterior circulatory system | 36 (5.7%) | 21 (10.2%) |
Continuous variables are represented by the median (interquartile range), and categorical variables are represented by the number of cases (percentage of the two groups)