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. 2021 Oct 31;45(2):800–811. doi: 10.1007/s10753-021-01585-x

Fig. 2.

Fig. 2

Increased neutrophil elastase release in COVID-19 patients. A Freshly isolated neutrophils from COVID-19 patients release more elastase at baseline (no exogenous stimulation) than neutrophils from healthy donors. B Neutrophils from COVID-19 patients release more elastase than neutrophils from healthy donors when stimulated with 1 nM PMA or 3 nM PMA (C). n = 14 healthy donors, n = 10 COVID-19 patients with minimal lung disease, n = 10 COVID-19 patients who developed mod/severe lung disease. One patient in each group did not receive stimulation with 1 nM PMA. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.