Table 1.
Patient and tumor characteristics based on final specimens
| EPP(N=191) | PD (N=193) | |
|---|---|---|
| No. (%) | No. (%) | |
|
Age at surgery, years Median (range) ≥49 years |
64 (18–81) 173 (91%) |
70 (30–86) 185 (96%) |
|
Gender Male Female |
169 (88%) 22 (12%) |
143 (74%) 50 (26%) |
|
ECOG performance status 0 1 2 |
42 (22%) 142 (74%) 7 (4%) |
53 (27%) 136 (70%) 4 (2%) |
|
Symptoms at presentation Weight loss >5% Chest pain |
78 (41%) 65 (34%) |
74 (38%) 76 (39%) |
|
Pathological histological subtype Epithelioid Biphasic Sarcomatoid Desmoplastic |
109 (57%) 71 (37%) 10 (5%) 1 (<1%) |
109 (56%) 70 (36%) 13 (7%) 1 (<1%) |
|
Pathological lymph node stage pN0 pN1 pN2 pNx |
74 (39%) 36 (19%) 81 (42%) |
111 (58%) 8 (4%) 54 (28%) 20 (10%) |
|
Tumor volume (TV)a, cc Median (range) >200 cc |
311 (<1–4285) 118 (65%) |
141 (<1–4437) 75 (39%) |
|
Mesothelioma prognosis test (MPT) Good risk Poor risk |
177 (93%) 14 (7%) |
155 (80%) 38 (20%) |
|
Molecular subtype test Cluster E Cluster non-E (BE/BS/S) |
32 (17%) 159 (83%) |
48 (25%) 145 (75%) |
|
Neutrophil:Lymphoctye ratio (NLR) Median (range) NLR >3 |
3.9 (0.3–29.0) 136 (71%) |
3.2 (0.9–20.5) 107 (55%) |
|
White blood count, x109/L Median (range) |
8.0 (3.9–17.1) | 7.2 (3.0–25.1) |
|
Hemoglobin, g/L Median (range) |
127 (67–164) | 126 (69–173) |
|
Serum albumin, g/L Median (range) |
39 (21–49) | 39 (10–48) |
a
Tumor volume missing for 10 patients (EPP 9, PDC 1).