Table 1.
Clinicopathological parameter | CD68/CD4 | CD68/CD8 | CD68/CD20 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High/low | High/high | Low/high | Low/low | p value | High/low | High/high | Low/high | Low/low | p value | High/low | High/high | Low/high | Low/low | p value | |
Age at diagnosis (years) | 0.462 | 0.571 | 0.618 | ||||||||||||
< 60 | 11 | 15 | 14 | 12 | 13 | 14 | 14 | 11 | 13 | 13 | 14 | 12 | |||
≥ 60 | 17 | 10 | 13 | 15 | 12 | 14 | 11 | 18 | 18 | 9 | 17 | 11 | |||
Tumor size (cm) | 0.124 | 0.727 | 0.131 | ||||||||||||
≤ 2 | 13 | 15 | 21 | 17 | 13 | 18 | 16 | 19 | 15 | 13 | 24 | 14 | |||
> 2 | 15 | 10 | 6 | 10 | 12 | 10 | 9 | 10 | 16 | 9 | 7 | 9 | |||
Histological grade | 0.082 | 0.089 | 0.224 | ||||||||||||
I, II | 6 | 5 | 7 | 13 | 5 | 6 | 5 | 15 | 7 | 4 | 10 | 10 | |||
III | 22 | 20 | 20 | 14 | 16 | 26 | 16 | 18 | 24 | 18 | 21 | 13 | |||
Histology | 0.080 | 0.020 | 0.498 | ||||||||||||
IBC-NST | 19 | 19 | 21 | 18 | 17 | 21 | 20 | 19 | 20 | 18 | 21 | 18 | |||
IBC-NST with medullary pattern | 2 | 6 | 3 | 0 | 1 | 6 | 4 | 0 | 4 | 4 | 3 | 0 | |||
Ca with apocrine differentiation | 4 | 0 | 3 | 3 | 3 | 0 | 1 | 6 | 4 | 0 | 4 | 2 | |||
Metaplastic carcinoma | 2 | 0 | 0 | 4 | 3 | 1 | 0 | 2 | 2 | 0 | 2 | 2 | |||
ILC | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 0 | |||
IMP | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
Lymph node status | 0.578 | 0.532 | 0.729 | ||||||||||||
Absent | 13 | 15 | 18 | 19 | 9 | 19 | 14 | 23 | 17 | 11 | 21 | 16 | |||
Present | 11 | 6 | 7 | 6 | 8 | 9 | 6 | 7 | 9 | 8 | 8 | 5 | |||
N/A | 4 | 4 | 2 | 2 | 4 | 4 | 1 | 3 | 5 | 3 | 2 | 2 | |||
Mib-1 index | 0.065 | 0.043 | 0.068 | ||||||||||||
< 20% | 2 | 3 | 5 | 9 | 2 | 3 | 3 | 11 | 3 | 2 | 6 | 8 | |||
≥ 20% | 26 | 22 | 22 | 18 | 19 | 29 | 18 | 22 | 28 | 20 | 25 | 15 | |||
Unstained TILs | 0.198 | 0.022 | < 0.001 | ||||||||||||
Low (≤ 30%) | 17 | 9 | 15 | 17 | 16 | 12 | 9 | 21 | 22 | 4 | 10 | 22 | |||
High (> 30%) | 11 | 16 | 12 | 10 | 9 | 16 | 16 | 8 | 9 | 18 | 21 | 1 |
IBC-NST invasive breast carcinoma of no special type, Ca carcinoma, ILC invasive lobular carcinoma, IMP invasive micropapillary carcinoma, N/A not applicable, TILs tumor-infiltrating lymphocytes
χ2 test. Italic type indicates a statistically significant difference (p < 0.05)