Table 2.

Associations with clinicopathological parameters and TAMs versus TILs status

Clinicopathological parameter	CD163/CD4					CD163/CD8					CD163/CD20
	High/low	High/high	Low/high	Low/low	p value	High/low	High/high	Low/high	Low/low	p value	High/low	High/high	Low/high	Low/low	p value
Age at diagnosis (years)					0.511					0.571					0.924
< 60	12	15	14	11		13	14	14	11		13	14	13	12
≥ 60	15	11	12	17		12	14	11	18		14	12	14	15
Tumor size (cm)					0.168					0.727					0.213
≤ 2	12	19	17	18		13	18	16	19		15	16	21	14
> 2	15	7	9	10		12	10	9	10		12	10	6	13
Histological grade					< 0.001					< 0.001					0.001
I, II	2	4	8	17		3	3	8	17		4	2	12	13
III	25	22	18	11		22	25	17	12		23	24	15	14
Histology					0.038					0.020					0.717
IBC-NST	19	19	21	18		17	21	20	19		19	19	20	19
IBC-NST with medullary pattern	1	6	3	1		1	6	4	0		2	5	2	2
Ca with apocrine differentiation	2	1	2	5		3	0	1	6		2	1	3	4
Metaplastic carcinoma	0	0	0	2		3	1	0	2		3	1	1	1
ILC	0	0	0	2		0	0	0	2		0	0	1	1
IMP	1	0	0	0		1	0	0	0		1	0	0	0
Lymph node status					0.357					0.569					0.490
Absent	18	15	12	20		12	15	18	20		13	14	18	20
Present	6	7	12	5		9	10	5	6		10	9	7	4
N/A	2	4	3	3		4	3	2	3		4	3	2	3
Mib-1 index					0.324					0.124					0.168
< 20%	4	2	6	7		4	2	4	9		5	1	7	6
≥ 20%	23	24	20	21		21	26	21	20		22	25	20	21
Unstained TILs					0.223					0.022					< 0.001
Low (≤ 30%)	18	10	14	16		16	12	9	21		22	6	8	22
High (> 30%)	9	16	12	12		9	16	16	8		5	20	19	5

IBC-NST invasive breast carcinoma of no special type, Ca carcinoma, ILC invasive lobular carcinoma, IMP invasive micropapillary carcinoma, N/A not applicable, TILs tumor-infiltrating lymphocytes

χ² test. Italic type indicates a statistically significant difference (p < 0.05)