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. 2021 Oct 30;12(11):1031. doi: 10.1038/s41419-021-04326-y

Table 2.

Characteristics of the different groups’ mice.

Group db/m db/db Cont db/db+ AdipoRon p* p#
n 12 12 12
Body weight (g) 29.8 ± 1.5 53.3 ± 5.2 51.5 ± 3.2 <0.0001 0.4531
Kidney weight (mg) 203 ± 5.8 204.7 ± 7.3 203 ± 9.2 0.8471 0.8471
Blood glucose (mmol/L) 8.5 ± 0.5 29.89 ± 3.6 21.7 ± 3.7 <0.0001 <0.0001
HbA1c (%) 4.1 ± 0.2 9.2 ± 0.4 8.6 ± 0.1 <0.0001 <0.0001
Triglyceride (mmol/L) 0.98 ± 0.2 1.96 ± 0.2 1.63 ± 0.3 <0.0001 0.0017
Total cholesterol (mmol/L) 1.43 ± 0.2 3.46 ± 0.3 3.2 ± 0.4 <0.0001 0.13
Scr (μmol/L)) 16.6 ± 2.9 19.1 ± 3.6 17.8 ± 3.3 0.1641 0.6
24 h albuminuria (mg/day) 10.17 ± 1.7 222.8 ± 35.2 157.4 ± 20.7 <0.0001 <0.0001
Serum adiponectin (μg/mL) 10.9 ± 0.8 4.6 ± 0.4 4.7 ± 0.5 <0.0001 0.9156

Values are the mean ± SD.

p*: db/m versus db/db; p#: db/db versus db/db + AdipoRon.

HBA1c glycosylated hemoglobin, Scr serum creatinine.