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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Comparison 10. Comparison: misoprostol versus gemeprost.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Induction to abortion interval 3 249 Mean Difference (IV, Fixed, 95% CI) 8.73 [5.11, 12.35]
1.1 Misoprostol, 100 mcg, versus gemeprost 1 55 Mean Difference (IV, Fixed, 95% CI) 8.60 [3.11, 14.09]
1.2 Misoprostol, 200 mcg versus gemeprost 1 54 Mean Difference (IV, Fixed, 95% CI) 13.3 [7.90, 18.70]
1.3 Misoprostol, 400 mcg, versus gemeprost 1 140 Mean Difference (IV, Fixed, 95% CI) ‐8.90 [‐19.65, 1.85]
2 Abortion within 24 hours 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 2.83 [1.33, 6.02]
2.1 Misoprostol, 400 mcg, versus gemeprost 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 2.83 [1.33, 6.02]
3 Blood loss (mL) 3 249 Mean Difference (IV, Fixed, 95% CI) ‐23.75 [‐47.80, 0.30]
3.1 Misoprostol, 100 mcg, versus gemeprost 1 55 Mean Difference (IV, Fixed, 95% CI) ‐61.0 [‐145.71, 23.71]
3.2 Misoprostol, 200 mcg, versus gemeprost 1 54 Mean Difference (IV, Fixed, 95% CI) ‐146.0 [‐219.02, ‐72.98]
3.3 Misoprostol, 400 mcg, versus gemeprost 1 140 Mean Difference (IV, Fixed, 95% CI) ‐3.70 [‐30.40, 23.00]
4 Surgical evacuation 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.94 [0.48, 1.85]
4.1 Misoprostol, 400 mcg, versus gemeprost 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.94 [0.48, 1.85]
5 Pain 2 109 Odds Ratio (M‐H, Fixed, 95% CI) 0.23 [0.10, 0.52]
5.1 Misoprostol, 100 mcg, versus gemeprost 1 55 Odds Ratio (M‐H, Fixed, 95% CI) 0.22 [0.07, 0.71]
5.2 Misoprostol, 200 mcg, versus gemeprost 1 54 Odds Ratio (M‐H, Fixed, 95% CI) 0.23 [0.07, 0.77]
6 Nausea 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.80 [0.38, 1.70]
6.1 Misoprostol, 400 mcg, versus gemeprost 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.80 [0.38, 1.70]
7 Vomiting 3 249 Odds Ratio (M‐H, Fixed, 95% CI) 0.38 [0.21, 0.67]
7.1 Misoprostol, 100 mcg, versus gemeprost 1 55 Odds Ratio (M‐H, Fixed, 95% CI) 0.33 [0.10, 1.06]
7.2 Misoprostol, 200 mcg, versus gemeprost 1 54 Odds Ratio (M‐H, Fixed, 95% CI) 0.15 [0.04, 0.62]
7.3 Misoprostol, 400 mcg, versus gemeprost 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.55 [0.25, 1.18]
8 Diarrhoea 3 249 Odds Ratio (M‐H, Fixed, 95% CI) 0.31 [0.17, 0.58]
8.1 Misoprostol, 100 mcg, versus gemeprost 1 55 Odds Ratio (M‐H, Fixed, 95% CI) 0.04 [0.00, 0.68]
8.2 Misoprostol, 200 mcg, versus gemeprost 1 54 Odds Ratio (M‐H, Fixed, 95% CI) 0.18 [0.03, 0.91]
8.3 Misoprostol, 400 mcg, versus gemeprost 1 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.48 [0.23, 0.99]