Comparison 12. Comparison: misoprostol, vaginal versus oral.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Induction to abortion interval	3		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	2	196	Mean Difference (IV, Fixed, 95% CI)	‐6.04 [‐8.51, ‐3.58]
1.2 Misoprostol, 400 mcg vaginal versus 200 mcg oral	1	114	Mean Difference (IV, Fixed, 95% CI)	‐14.9 [‐23.33, ‐6.47]
2 Abortion within 24 hours	1	114	Odds Ratio (M‐H, Fixed, 95% CI)	9.6 [3.74, 24.66]
2.1 Misoprostol 400 mcg vaginal versus 200 mcg oral	1	114	Odds Ratio (M‐H, Fixed, 95% CI)	9.6 [3.74, 24.66]
3 Blood loss (mL)	1	114	Mean Difference (IV, Fixed, 95% CI)	24.00 [‐70.90, 118.90]
3.1 Misoprostol 400 mcg vaginal versus 200 mcg oral	1	114	Mean Difference (IV, Fixed, 95% CI)	24.00 [‐70.90, 118.90]
4 Pain	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.29 [0.08, 1.07]
4.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.29 [0.08, 1.07]
5 Surgical evacuation	3	310	Odds Ratio (M‐H, Fixed, 95% CI)	0.63 [0.34, 1.17]
5.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	2	196	Odds Ratio (M‐H, Fixed, 95% CI)	0.60 [0.30, 1.21]
5.2 Misoprostol 400 mcg vaginal versus 200 mcg oral	1	114	Odds Ratio (M‐H, Fixed, 95% CI)	0.74 [0.20, 2.67]
6 Nausea	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.41 [0.18, 0.93]
6.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.41 [0.18, 0.93]
7 Vomiting	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.43 [0.19, 0.98]
7.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	0.43 [0.19, 0.98]
8 Diarrhoea	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	1.23 [0.39, 3.85]
8.1 Misoprostol 400 mcg vaginal versus 400 mcg oral	1	108	Odds Ratio (M‐H, Fixed, 95% CI)	1.23 [0.39, 3.85]