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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Comparison 17. Comparison: low dose versus high dose of misoprostol.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Induction to abortion interval 2 113 Mean Difference (IV, Fixed, 95% CI) 1.29 [‐3.12, 5.69]
1.1 100 mcg versus 200 mcg 1 53 Mean Difference (IV, Fixed, 95% CI) ‐4.70 [‐11.19, 1.79]
1.2 400 mcg versus 600 mcg 1 60 Mean Difference (IV, Fixed, 95% CI) 6.4 [0.40, 12.40]
2 Pain 2 113 Odds Ratio (M‐H, Fixed, 95% CI) 0.75 [0.29, 1.95]
2.1 100 mcg versus 200 mcg 1 53 Odds Ratio (M‐H, Fixed, 95% CI) 0.93 [0.32, 2.75]
2.2 400 mcg versus 600 mcg 1 60 Odds Ratio (M‐H, Fixed, 95% CI) 0.31 [0.03, 3.17]
3 Nausea 1 60 Odds Ratio (M‐H, Fixed, 95% CI) 0.64 [0.10, 4.15]
3.1 400 mcg versus 600 mcg 1 60 Odds Ratio (M‐H, Fixed, 95% CI) 0.64 [0.10, 4.15]
4 Vomiting 2 113 Odds Ratio (M‐H, Fixed, 95% CI) 1.42 [0.42, 4.85]
4.1 100 mcg versus 200 mcg 1 53 Odds Ratio (M‐H, Fixed, 95% CI) 2.19 [0.49, 9.88]
4.2 400 mcg versus 600 mcg 1 60 Odds Ratio (M‐H, Fixed, 95% CI) 0.48 [0.04, 5.63]
5 Diarrhoea 2 113 Odds Ratio (M‐H, Fixed, 95% CI) 0.53 [0.11, 2.58]
5.1 100 mcg versus 200 mcg 1 53 Odds Ratio (M‐H, Fixed, 95% CI) 0.18 [0.01, 3.90]
5.2 400 mcg versus 600 mcg 1 60 Odds Ratio (M‐H, Fixed, 95% CI) 1.0 [0.13, 7.60]