Armatage 1996.

Methods	Patients were randomised into 2 groups using sealed sequentially numbered envelopes.
Participants	99 pregnant women (group I: 50, group II: 49) Inclusion criteria: uncomplicated pregnancies, between 12‐20 weeks gestation. Exclusion criteria: multiple pregnancy, known fetal abnormality, significant maternal illness.
Interventions	Group I: gemeprost pessaries at 3‐hourly intervals up to a maximum of 5 in 24 hours, until fetal expulsion. Group II: gemeprost pessaries at 6‐hourly intervals until fetal expulsion. Where abortion did not occur within 48 hours, an intravenous oxytocin infusion was commenced unless delivery was deemed imminent.
Outcomes	Primary outcome: abortion interval, abortion rates. Secondary outcomes: analgesia, side‐effects, surgical evacuations.
Notes	Definition of abortion: expulsion of the fetus. Following delivery of the fetus, intramuscular Syntometrine (ergometrine maleate 500 μg and oxytocin 5 iu, Sandez Products Limited) was given. One women received a blood transfusion (group 1). Women underwent surgical evacuation if the placenta was retained or did not appear intact.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ adequate
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.