Borgida 1995.

Methods	Sequentially numbered, sealed, opaque envelopes containing indicator cards and were opened at enrolment. The randomisation sequence was determined by a random‐number table and a block size of 6.
Participants	50 pregnant women (group I: 27, group II: 23) Inclusion criteria: abnormal 14‐24 weeks pregnancy, age 18‐45 years. Exclusion criteria: allergies to medications, cardiac/pulmonary/renal disease.
Interventions	All: pre‐med (25 mg diphenhydramine hydrochloride, 10 mg metoclopramide hydrochloride, 5 mg diphenoxylate hydrochloride, 650 mg acetaminophen) every 4‐6 hours + 30 minutes after first dose: Group I: 250 μg IM 15M PGF2α injections every 3 hours; Group II: 20 mg intravaginal PGE2 every 3 hours. After delivery, all patients received oxytocin 40 U/L, and if the placenta was not delivered within approximally 2 hours or excessive bleeding occurred, a curettage was performed.
Outcomes	Primary outcomes: induction to abortion interval, abortion within 24 hours. Secondary outcomes: surgical evacuation, side‐effects.
Notes	Definition of abortion: expulsion of fetus. No major complications reported.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ adequate
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.