el‐Refaey 1993.
Methods | Randomisation by sealed envelope selection. | |
Participants | 60 pregnant women (group I: 30, group II: 30) Inclusion criteria: 13‐20 weeks gestation. Exclusion criteria: none reported. |
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Interventions | 600mg mifepristone (36‐48 hours later followed by): Group I: misoprostol 400 μg orally, every 3 hrs, max 3 doses. If abortion did not occur: two further doses of vaginal gemeprost 1 mg, every 3 hrs; Group II: gemeprost 1 mg pessaries vaginally, every 3 hrs, max 5 doses. |
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Outcomes | Primary outcome: abortion within 24 hours. Secondary outcomes: surgical evacuation, side‐effects. |
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Notes | Definition of abortion: expulsion of fetus and placenta. No information was provided regarding the policy of evacuation of the uterus. No major complications reported. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | A ‐ adequate |
Blinding? All outcomes | High risk | |
Free of other bias? | Low risk | No statistically significant differences between the groups in terms of maternal age, gestational age and parity. |