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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

el‐Refaey 1993.

Methods Randomisation by sealed envelope selection.
Participants 60 pregnant women (group I: 30, group II: 30)
Inclusion criteria: 13‐20 weeks gestation.
Exclusion criteria: none reported.
Interventions 600mg mifepristone (36‐48 hours later followed by):
Group I: misoprostol 400 μg orally, every 3 hrs, max 3 doses. If abortion did not occur: two further doses of vaginal gemeprost 1 mg, every 3 hrs;
Group II: gemeprost 1 mg pessaries vaginally, every 3 hrs, max 5 doses.
Outcomes Primary outcome: abortion within 24 hours.
Secondary outcomes: surgical evacuation, side‐effects.
Notes Definition of abortion: expulsion of fetus and placenta.
No information was provided regarding the policy of evacuation of the uterus.
No major complications reported.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ adequate
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No statistically significant differences between the groups in terms of maternal age, gestational age and parity.