El‐refaey 1995.

Methods	Randomisation using computer‐generated random number tables. A series of numbered, sealed, opaque envelopes was prepared containing allocation.
Participants	69 pregnant women (group I: 34, group II: 35) Inclusion criteria: 13‐20 weeks gestation. Exclusion criteria: none reported.
Interventions	All: mifepristone 600 μg orally + vaginal misoprostol 600 μg (first dose) Group I: oral misoprostol 400 μg every 3 hours, max 5d; Group II: vaginal misoprostol 400 μg every 3 hours, max 5d. If after the fifth dose, abortion had not occurred, 1 mg gemeprost was administered the next morning.
Outcomes	Primary outcomes: induction to abortion interval, abortion within 24 hours. Secondary outcomes: side‐effects.
Notes	Definition of abortion: abortion occurring after the fifth dose. One patient suffered from rigours, vomiting and eruption of a maculopapular rash following the administration of 600 μg misoprostol. If the placenta was retained, the uterus was surgically evacuated.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ adequate
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.