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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Ho 1996.

Methods Randomisation schedule was prepared as described by Meinert. Sealed envelopes with serial numbers on the front and containing the group to which the woman was randomised were opened at recruitment.
Participants 50 pregnant women (group I: 25, group II: 25)
Inclusion criteria: 14‐20 weeks gestation.
Exclusion criteria: regular use of prescription drugs, IUD in utero, nursing mothers, multiple pregnancies, heavy smokers.
Interventions All: 200mg mifepristone orally (36‐48 hours later):
Group I: 400 μg misoprostol orally, every 3 h, max 5 doses;
Group II: 1mg gemeprost vaginally, every 6 hours, max 4 doses.
The patient was reassessed after 24h. If there were no signs or symptoms suggestive of imminent abortion, the pregnancy was terminated with 1 mg gemeprost every 3 hours.
Outcomes Primary outcome: induction of abortion interval, abortion within 24 hours.
Secondary outcomes: side‐effects, uterine contractions, blood pressure, pulse rate.
Notes Definition of abortion: not specified.
If the placenta was incomplete, an evacuation of the uterus was carried out.
No major complications reported.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ adequate
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No statistically significant differences between the groups in terms of maternal age, gestational age and gravidity.