Inan 1997.
Methods | Randomly assigned. | |
Participants | 78 pregnant women (group I: 48, group II: 30) Inclusion criteria: 13‐24 weeks gestation, Bishop score <4. Exclusion criteria: none described. |
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Interventions | Group I: extra‐amniotic ethacridine lactate (Rivanol). A No 16 Foley catheter was placed into the uterus. Following inflammation of the balloon of the catheter to 20‐30 ml, an average of 10 ml of 0.1 % sterile ethacridine lactate solution per gestational week was instilled extra‐amniotically. The catheter was left in place for 24 hours, if not expelled earlier. Group II: 2.5 ml gel containing 0.5 mg PGE2, intracervical (Cerviprost 0.5 mg gel Organon). Group III: extra‐amniotic ethacridine lactate combined with oxytocin infusion. 10‐20 units/5% DW IV oxytocin induction was started within 2‐4 hours following the ethacridine lactate instillation. For analyses, we did not include group III. |
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Outcomes | Successful abortion rates, side‐effects. | |
Notes | Definition of abortion: Complete evacuation of fetus and placental tissues from the uterus within 24 hours. No major complications described. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | B ‐ unclear |
Blinding? All outcomes | High risk | |
Free of other bias? | Low risk | No statistically significant differences between the groups in terms of maternal age, gestational age and parity. |