Mehta 1975 a.
Methods | Prepared envelopes indicating one of the methods were picked up serially; the investigators being blind to what the envelopes contained till they opened them. | |
Participants | 67 pregnant women (group I: 33, group II: 34) Inclusion criteria: 15‐20 weeks gestation. Exclusion criteria: none given. |
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Interventions | Group I: 20% hypertonic saline, 200 ml. Group II: single dose, 50mg PGF2α. |
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Outcomes | Abortion rates, side‐effects. | |
Notes | Definition of abortion: when complete (spontaneous evacuation of all products of conception) or incomplete abortion (total or partial retainment of placenta or membranes) occurred within 72 hours. No information was provided regarding the policy of evacuation of the uterus. One women in the single dose PGF2α group received a blood transfusion. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | A ‐ adequate |
Blinding? All outcomes | High risk | |
Free of other bias? | Low risk | No statistically significant differences between the groups in terms of maternal age, gestational age and parity. |