Mehta 1975 b.

Methods	Prepared envelopes indicating one of the methods were picked up serially; the investigators being blind to what the envelopes contained till they opened them.
Participants	66 pregnant women (group I: 33, group II: 33) Inclusion criteria: 15‐20 weeks gestation. Exclusion criteria: none given.
Interventions	Group I: 20% hypertonic saline, 200 ml. Group II: multiple doses of 25mg PGF2α, given at 0 hours and 6 hours. Similar doses were instilled at 24 hours and 30 hours when necessary.
Outcomes	Abortion rates, side‐effects.
Notes	Definition of abortion: when complete (spontaneous evacuation of all products of conception) or incomplete abortion (total or partial retainment of placenta or membranes) occurred within 72 hours. No information was provided regarding the policy of evacuation of the uterus. One women in the single dose PGF2α group received a blood transfusion.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ adequate
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.