Muzsnai 1979 d.

Methods	Random assignment. After completion of 50 patients in group I and II, the remaining patients were assigned to both groups, because of favourable outcome.
Participants	285 pregnant women (group I: 205, group II: 80) Inclusion criteria: 16‐24 weeks of gestation. Exclusion criteria: history of uterine surgery.
Interventions	Group I: PGF2α (20mg) + 25 mL 20% NaCl (5g), intra‐amniotic. All amniotic fluid removed. Group II: PGF2α (20mg) + 100 mL 10% NaCl (10g), intra‐amniotic.  100mL amniotic fluid removed. All patients received i.v. oxytocin stimulation 40 mU/min.
Outcomes	Instillation to abortion time, abortion interval, complications, side‐effects.
Notes	Definition of abortion: none given. Incomplete abortion: if placenta was not expelled within 2h after delivery of the fetus, of if haemorrhage occurred. Failure of abortion: if fetus was not expelled within 48h. The procedure was then repeated. Instillation abortion interval: time from amniocentesis to expulsion of fetus. No major complications described.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	B ‐ unclear
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.